Niacinamide vs. Hyaluronic Acid: The Ultimate Battle 

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In the realm of skincare heavyweights, two ingredients have emerged as favorites: niacinamide and hyaluronic acid.

These powerhouses have gained immense popularity for their exceptional abilities to address various skin concerns.

A woman in a bathrobe is putting lotion on her face.

Today we’ll embark on a journey of comparing and exploring the unique qualities of niacinamide and hyaluronic acid to discover the amazing benefits and extraordinary capabilities of both ingredients.

We will uncover the similarities and differences between niacinamide vs. hyaluronic acid in this ultimate battle.

Join us as we delve into the world of these skincare giants and decipher which one reigns supreme for your skin’s needs and deserves the crown in your skincare kingdom.

Niacinamide vs. Hyaluronic Acid: A Peek Into Their Similarities and Differences

NiacinamideHyaluronic Acid
DefinitionA form of vitamin B3 that has several benefits for the skinA naturally occurring substance that attracts and retains moisture
Source Found in various food sources and supplementsNaturally present in the body and derived from bacterial fermentation or plant sources
FunctionRegulates cellular processes and improves skin barrier function.Attracts and retains water molecules, providing deep hydration.
Key Benefits• Regulates sebum production
• Improves skin texture and tone
• Reduces redness and hyperpigmentation
• Provides intense hydration 
• Plumps and firms the skin 
• Improves skin elasticity
Skin Concerns• Acne
• Uneven skin tone
• Aging skin and fine lines
• Dehydrated skin
• Fine lines and wrinkles
• Dull complexion
CompatibilityBest for oily, combination, and acne-prone skinBest for dry to normal skin types

What Is Niacinamide?

Niacinamide, a type of vitamin B3, is a water-soluble vitamin that plays a crucial role in maintaining healthy skin.

It’s sourced from various food sources such as meat, fish, legumes, and grains.

However, it’s now often synthetically produced, ensuring its availability for skincare formulations.

It has become a versatile ingredient in serums and toners because it offers a wide range of benefits for various skin types and concerns.

Since then, this multifaceted compound gained significant recognition for its remarkable benefits in promoting healthy, radiant skin.

A bottle with a drop of serum on a white surface.

Key Benefits of Niacinamide for the Skin

Regulates Sebum Production

In a 2006 study, the topical application of a 2% concentration of niacinamide showed a significant reduction in excess oil production among test subjects. 

This makes it a valuable asset for those with oily or acne-prone skin. 

By balancing sebum levels, niacinamide not only stops excessive oiliness but also helps prevent clogged pores and breakouts that result from oil buildup, promoting a clearer and more balanced complexion.

Improves Skin Texture 

Niacinamide works to improve skin texture by minimizing pores and boosting the production of collagen, the protein responsible for maintaining the skin’s elasticity. 

As a result, it refines the skin’s texture, making it appear smoother, softer, and more supple.

Additionally, niacinamide helps reduce the appearance of fine lines, wrinkles, and enlarged pores, promoting a more youthful and rejuvenated appearance.

Reduces Hyperpigmentation and Redness

Niacinamide is also renowned for its skin-brightening properties.

It inhibits the transfer of melanin from the melanocytes — the cells that produce melanin — onto the skin cells in the epidermis. 

This helps reduce the appearance of hyperpigmentation, dark spots, and uneven skin tone.

Additionally, niacinamide’s anti-inflammatory properties calm and soothe the skin, reducing redness, irritation, and sensitivity.

Best Niacinamide Products You Should Add to Your Skincare Routine

Best Niacinamide Product for All Skin Types

Advanced Clinicals Niacinamide Serum

A professional strength serum designed to slow down aging, treat dark spots, and restore your skin’s radiance. 

Primary Benefits: Fights visible signs of aging; removes dark spots and age spots; brightens and clarifies skin


  • 5% niacinamide with skin-brightening capabilities
  • Zinc and magnesium with anti-aging properties
  • Aloe vera and fruit extracts for skin hydration

Elevate your skincare routine with the Advanced Clinicals Niacinamide Serum.

This ultra-hydrating formula targets fine lines and wrinkles while giving your skin the TLC it deserves.

Packed with 5% niacinamide, it rewinds the clock to restore your youthful glow and clear complexion. 

Best Niacinamide Product for Sensitive Skin

InstaSkincare Niacinamide Facial Serum

Bid adieu to dark spots, redness, and dryness with the InstaSkincare Niacinamide Facial Serum, a powerhouse formula designed to rejuvenate and nourish your skin.

Primary Benefits: Hydrating and nourishing; fades post-inflammatory hyperpigmentation; smoothens and evens out skin tone


  • 3% niacinamide to boost collagen production 
  • Zinc oxide for sun protection
  • Vitamin E to prevent cell damage 
  • Citric acid to protect and reverse photoaging 
  • Vegan and cruelty-free 

Experience visible results within 14 days of regular use.

With 3% niacinamide, the InstaSkincare Niacinamide Facial Serum improves skin texture and promotes a more even skin tone. 

Infused with zinc, this serum also calms irritation and reduces redness, making it suitable for sensitive skin. 

Best Niacinamide Product for Acne-Prone and Aging Skin

Naturium Niacinamide Face Serum

Natarium’s potent serum with 12% niacinamide targets signs of aging and pesky blemishes for healthier, younger-looking skin. 

Primary Benefits: Shrinks pores; reduces dark spots, evens out skin texture and tone; improves the appearance of fine lines and wrinkles


  • 12% niacinamide to fade dark spots and shrink pores
  • 2% zinc to refine skin texture
  • Vegan and cruelty-free 

This serum is the ultimate game-changer for your skin.

Fine lines, wrinkles, dark spots, and hyperpigmentation? Not on this serum’s watch! 

Natarium Face Serum reverses signs of aging and lightens those stubborn spots, giving you a more even, radiant complexion.

With this product, you can face the world with confidence.

What Is Hyaluronic Acid?

Hyaluronic acid is a sugar molecule that acts as a powerful humectant, meaning it has a unique ability to attract and retain moisture.

Did you know that your body produces HA? Yes, that’s right. Hyaluronic acid is a naturally occurring compound in the body.

However, the level of hyaluronic acid we produce diminishes as we age, which is where skincare products with this ingredient come to the rescue. 

Hyaluronic acid in skincare products is derived through a process called biofermentation from natural sources like bacteria or yeast, ensuring it’s safe, pure, and suitable for even the most sensitive skin.

A drop of face serum is being poured into a a beige surface

Key Benefits of Hyaluronic Acid for the Skin

Intense Hydration and Moisture Retention

Hyaluronic acid is like a drink of water for your skin.

It has the extraordinary ability to hold up to 1,000 times its weight in water, creating a reservoir of hydration within your skin.

Imagine it as a moisture magnet, attracting and binding to water molecules to maintain your skin’s optimal hydration levels, making it plump and supple.

Plumping Effect

Hyaluronic acid works wonders in the fight against fine lines and wrinkles too.

As it replenishes lost moisture and hydrates your skin, it provides a plumping effect, filling in the creases and making them less noticeable. 

Improvement in Overall Skin Elasticity

As we age, our skin’s elasticity takes a hit, leaving it prone to sagging and drooping. 

By offering deep hydration and boosting moisture levels, hyaluronic acid can also support the skin’s natural elasticity, helping it maintain its bounce, firmness, and resilience. 

Best Hyaluronic Acid Products You Should Add to Your Beauty Regimen

Best Hyaluronic Acid Product for Oily and Combination Skin

Eclat Pure Hyaluronic Acid Face Serum

Ecla’s potent low-weight HA serum penetrates three times deeper into your skin for intense hydration that lasts up to 16 hours.   

Primary Benefits: Helps users achieve optimal skin hydration; maintains moisture for up to 16 hours; reduces fine lines and wrinkles in six weeks


  • 2.5% low-weight hyaluronic acid for deeper hydration
  • Uses vitamins C and E to nourish the skin 
  • Contains flavonoids that boost collagen production

Eclat Pure Hyaluronic Acid Face Serum is the ultimate elixir of hydration that keeps the skin dewy and supple all day.

This hyaluronic acid serum offers ultimate hydration to give you plumper, firmer skin like never before. 

As it replenishes moisture, it fills in fine lines and wrinkles, smoothing them out to reveal a more youthful look.

Best Drugstore Hyaluronic Acid Product

L'Oreal Paris Revitalift 1.5% Pure Hyaluronic Acid Face Serum

This powerful serum is packed with the goodness of high- and low-weight hyaluronic acid for the ultimate hydration your skin craves.

Primary Benefits: Hydrates and plumps the skin; smoothens and brightens the skin; fights signs of aging


  • 1.5% pure high and low-weight hyaluronic acid for immediate visible results
  • Contains vitamin C to reverse signs of aging
  • Paraben-, mineral oil-, synthetic dye-, and fragrance-free

This serum minimizes fine lines and wrinkles significantly!

Formulated with a potent concentration of 1.5% pure hyaluronic acid, this serum from L’Oreal Paris delivers intense and long-lasting hydration.

It penetrates into the deeper layers of the skin, replenishing moisture loss while making your skin more radiant.

Best Hyaluronic Acid Product for All Skin Types

Asterwood Pure Hyaluronic Acid Serum for Face

Asterwood offers a no-frills, 100% pure hyaluronic acid serum to hydrate your skin like no other.

Primary Benefits: Deeply hydrates and draws moisture into the skin; enhances skin elasticity; reduces and protects against signs of aging


  • 100% pure vegan hyaluronic acid for unmatched hydration 
  • Fragrance-free
  • Cruelty-free

You can easily incorporate this serum into your daily skincare routine.

Introducing Asterwood Pure Hyaluronic Acid Serum for Face, the skincare must-have that will leave your skin feeling oh-so-soft and nourished.

Not only does it give your skin a boost of hydration, but it also draws more moisture and seals it into the skin. This ensures your skin stays well-hydrated all day long!

Niacinamide vs. Hyaluronic Acid: Similarities and Differences

While hyaluronic acid and niacinamide differ in their functions and mechanisms of action, they also share some similarities.

Let’s delve into the similarities and differences between niacinamide and hyaluronic acid to gain a better understanding of their roles in your skincare routine.

Similarities of Niacinamide and Hyaluronic Acid 

Both niacinamide and hyaluronic acid can do the following:

  • Help you achieve healthy and younger-looking skin
  • Contribute to overall skin health and hydration
  • Suit various skin types, including sensitive skin
  • Provide various skincare benefits when used in skincare formulations, including niacinamide and hyaluronic acid moisturizers, serums, and masks

Differences Between Hyaluronic Acid and Niacinamide 

Understanding what distinguishes hyaluronic acid and niacinamide from each other is essential in choosing the right ingredients for your skincare routine.

Let’s take a closer look at their differences below. 

Skin Concerns

These two ingredients address different skin concerns.

Hyaluronic acid is renowned for its exceptional ability to act as a moisture magnet that attracts and retains water, addressing issues related to dryness and dullness.

On the other hand, niacinamide focuses on regulating oil production, improving uneven or bumpy skin texture, and reducing hyperpigmentation and redness. 

Its multifaceted approach makes it a valuable asset for individuals dealing with acne, fine lines, and dark spots.

Short- and Long-Term Effects

Both niacinamide and hyaluronic acid require consistent use but for different reasons. 

The effects of hyaluronic acid are immediate, providing instant hydration and a plumping effect. It gives the skin a youthful and refreshed appearance almost instantly. 

However, it should be noted that the hydration it provides is temporary. As such, it must be used regularly to help maintain the skin’s optimal hydration levels. 

In contrast, niacinamide’s results are more gradual but impactful in the long run. 

You may not see immediate improvements in the skin concerns you wish to address with just one application of niacinamide. 

However, with consistent use, its steady and effective approach allows it to refine skin tone and texture over time. 

Suitability for Different Skin Types

Niacinamide is generally well-tolerated by most skin types, but it’s especially beneficial for oily and combination skin that’s prone to acne.

It is non-irritating, and it has soothing properties that can help calm inflammation and redness.

Meanwhile, hyaluronic acid is most suitable for dry and sensitive skin types.

That said, it’s also great for oily skin, as it’s easily absorbed by the skin without clogging pores.

Hyaluronic Acid vs. Niacinamide: Addressing Specific Skin Concerns 

In this section, we will take a closer look at how using niacinamide and hyaluronic acid targets common skin issues and which of them can provide a more effective solution for each concern. 

1. Niacinamide vs. Hyaluronic Acid for Dry and Dehydrated Skin 

While niacinamide reinforces the skin’s protective barrier to prevent moisture loss, it is not a hydrating agent in and of itself. 

On the other hand, hyaluronic acid is known for its ability to hydrate the skin instantly.

Aside from sealing in moisture to prevent moisture loss throughout the day, it also provides an instant hydrating effect. 

So when it comes to addressing dryness issues, hyaluronic acid comes out ahead of niacinamide.

Winner: Hyaluronic Acid

2. Niacinamide vs. Hyaluronic Acid for Fine Lines and Wrinkles 

Niacinamide works by promoting collagen production and enhancing the skin’s natural barrier, which directly improves loose, wrinkled, and sagging skin.

On the other hand, hyaluronic acid focuses on providing intense hydration, which can plump up the skin temporarily. 

In this regard, niacinamide may be a better option because it has a more direct and long-term impact on reducing the appearance of fine lines and wrinkles.

Winner: Niacinamide

3. Niacinamide vs. Hyaluronic Acid for Acne and Oiliness

Niacinamide, with its sebum-regulating and anti-inflammatory properties, provides a multifunctional solution for oily and acne-prone skin. 

It helps control excess oil, reduces redness, and calms irritation. 

Meanwhile, hyaluronic acid is not directly involved in sebum regulation. But it does contribute to balanced sebum production by maintaining the skin’s moisture balance. 

By keeping the skin properly hydrated, it helps prevent the skin from overproducing oil as a compensatory response to dehydration.

In this way, it’s beneficial for acne because it helps prevent excess oil that can cause the issue. 

However, it’s evident that niacinamide is a much better option for directly addressing acne and oiliness.

Winner: Niacinamide

4. Niacinamide vs. Hyaluronic Acid for Textured Skin and Uneven Skin Tone 

The topical application of niacinamide helps facilitate collagen production and shrink pores, leading to a more refined complexion. 

Additionally, niacinamide’s ability to inhibit melanin transfer contributes to reducing dark spots and hyperpigmentation, which promotes clearer skin. 

Meanwhile, hyaluronic acid takes center stage in delivering intense hydration and moisture retention to the skin.

This plumps and firms the skin, indirectly contributing to improved skin texture. 

Unfortunately, it can’t do much for improving hyperpigmentation. 

This means that if you want a more head-on approach to smoothening and evening out your skin, niacinamide is the main ingredient to consider.

Winner: Niacinamide

5. Niacinamide vs. Hyaluronic Acid for Rosacea 

While hyaluronic acid can be beneficial for those with rosacea because it supports overall skin health, niacinamide may be the better option for addressing the specific symptoms of this skin condition.

By calming the skin and improving its barrier function, niacinamide can help manage the redness and inflammation associated with rosacea and make the skin feel more soothed and comforted. 

Winner: Niacinamide

A young asian woman posing with her hand on her face.

Can I Use Niacinamide and Hyaluronic Acid Together?

Now that you know the similarities and differences between hyaluronic acid and niacinamide, you may be wondering whether you can combine niacinamide and hyaluronic acid serums together to maximize their benefits. 

So if you’re wondering, “Can I mix hyaluronic acid and niacinamide?” the answer is yes, absolutely!

In fact, hyaluronic acid and niacinamide together are an unbeatable duo in terms of hydrating, nourishing, and improving the overall health of your skin. 

To give you a better idea of how they do this, here’s a list of what these skincare allies can give your skin when they unite:

  • Enhanced hydration. Niacinamide improves the skin’s barrier function to prevent moisture loss, while hyaluronic acid attracts and retains moisture in the skin. 

    This means using them together will give your skin intense hydration. 
  • Improved skin texture. The combination of niacinamide’s skin-smoothing properties and hyaluronic acid’s plumping effects helps improve overall skin texture, leaving it soft and supple.
  • Brightened complexion. Niacinamide targets hyperpigmentation and uneven skin tone, while hyaluronic acid addresses dullness caused by dryness and adds a refreshing glow to your skin.
  • Reduced signs of aging. Niacinamide aids in diminishing fine lines and wrinkles, while hyaluronic acid enhances skin elasticity, improving sagging skin for a more youthful appearance.
  • Balanced sebum production. Niacinamide regulates sebum production, helping control oiliness and prevent breakouts. 

    Hyaluronic acid can help niacinamide in this regard by keeping the skin adequately hydrated to ensure it only produces the appropriate amount of oil.

By combining the powers of niacinamide and hyaluronic acid, you can achieve hydrated, smooth, and radiant skin while addressing multiple skin concerns simultaneously.


Should I Use Hyaluronic Acid Before or After Niacinamide?

It is recommended to apply hyaluronic acid first to hydrate your skin and lock in moisture.

After allowing your hyaluronic acid serum to absorb for a few minutes, top it off with niacinamide serum to protect the outer layer of your skin and prevent moisture loss.

But before applying niacinamide or hyaluronic acid, be sure to wash your face with a good cleanser or face wash. 

This way, dirt and impurities on your skin won’t block them from penetrating into the skin’s deepest layers and keep you from getting the maximum benefits of these potent compounds.

Niacinamide Serum vs. Hyaluronic Acid Serum: Which is More Irritating?

In terms of potency concerning potential skin sensitivity, both niacinamide serums and hyaluronic acid serums are generally well-tolerated by most skin types. 

They are both generally gentle, making them suitable choices for individuals with sensitive skin.

That said, niacinamide has more of a tendency to cause irritation, itch, and redness. It may also create a burning sensation on the skin. 

If this happens to you, you can try using a lower concentration of niacinamide or use it less frequently. 

Also, check if you’re mixing it with ingredients like alpha hydroxy acids or beta hydroxy acids (AHAs or BHAs).

Combining niacinamide with these ingredients can lead to irritation, so it’s not recommended. 

As always, it’s best to consult with your dermatologist for a more thorough evaluation of whether the niacinamide product you’re using is right for you.

Niacinamide or Hyaluronic Acid: Which is Better for Your Skin? The Choice Is Yours

In this battle between niacinamide versus hyaluronic acid, we’ve revealed some key facts about these two skincare superheroes. 

Each  bring their own unique powers to the table, addressing different skin concerns with finesse. 

Niacinamide has proven its worth in regulating sebum production, improving skin texture and tone, and reducing hyperpigmentation and redness.

On the other hand, hyaluronic acid has wowed us with its intense hydration, plumping and firming effects, and overall improvement in skin elasticity. 

While we pitted these ingredients against each other, we also touched on the possibility of using them together, which turned out to be an unbeatable team. 

It turns out that niacinamide and hyaluronic acid offer countless benefits when used together!  

So whether you’re dealing with acne, dryness, or aging concerns, incorporating these ingredients into your skincare regimen can yield impressive results.

Remember to read product labels, follow usage instructions, and be patient, as skincare is a journey.

So go ahead and explore the vast array of products available and discover the power of niacinamide and hyaluronic acid for healthy, radiant skin.

Your skin will thank you!

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  • Stephanie Martin

    Stephanie Martin blends her beauty industry background with expertise in communications to lead in the fashion and beauty world. As a fashion and beauty editor, she is known for engaging and informative articles. Her lifelong passion for fashion, makeup, and hair shines through her work, earning her widespread respect among readers and clients. Stephanie's style, a mix of classic and contemporary, makes her a dynamic and influential figure in the industry, inspiring others with her knowledgeable and approachable insights.

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